Two people were taken to area hospitals following a single vehicle crash in North Port on Thursday afternoon.
Police say the driver of a 1999 Ford lost control on I-75 southbound at Kings Highway near milemarker 172 and hit a barrier.
The driver was ejected and his leg was amputated below the knee. Both he and his passenger were rushed to hospital in serious condition.
One lane of traffic was closed for most of the afternoon while the FHP investigated the crash.